DOI
https://doi.org/10.18849/ve.v4i3.196Abstract
PICO question
In three day event horses, does biannual routine influenza vaccination compared to annual routine influenza vaccination reduce performance levels?
Clinical bottom line
There is no evidence that biannual equine influenza vaccination compared to annual booster vaccination in three day event horses is associated with reduced performance.
A group of five studies published over an 11 year period from one were evaluated. In adult warmblood horses there is weak evidence that exercise in the 28 day period post booster vaccination for equine influenza and equine herpes virus 1 and 4 (EHV1&4), is associated with changes in physical and clinical pathophysiological parameters including total red blood cell (RBC) count, neutrophil and lymphocyte count, fibrinogen concentration and serum proteins. These changes occurred at variable time points in the 14 days post exercise and values were not outside the published reference ranges for the reporting laboratories where published. Athletic performance of the horses was not evaluated.
No recommendations for equine influenza vaccination protocols in three day event horses can be made from the evidence.
References
Goundasheva[sic], D., Chenchev, I., Katsarova, R., Karadiov, T., Tsachev, I., Barzey, G. (2005). "Changes in leukocyte and antibody response following exercise in horses with booster vaccination against influenza and herpes virus 4/1." Revue de Medecine Veterinaire 156(11): 527–532.
(A) Gundasheva, D. (2015). "Effect of exercise on erythron, heart and respiratory rates in horses vaccinated against equine herpes virus 4/1 and equine influenza virus." Comparative Clinical Pathology 24(6): 1565–1572. DOI: http://dx.doi.org/10.1007/s00580-015-2117-9
(B) Gundasheva, D. (2015). "Electrophoretic Analysis of Serum Proteins in Strenuously Trained Horses Revaccinated Against Equine Herpes Virus 4/1 and Equine Influenza Virus." Veterinarija ir Zootechnika 69(91): 18–25.
Gundasheva, D., & Georgieva, T. (2015). "Changes in some acute phase response parameters after physical exercise in horses with booster vaccination against equine herpes virus 4/1 and equine influenza virus." Veterinarija ir Zootechnika 70(92): 22–28.
Sotirov, L., Goundasheva, D., Dzheleboy, P. (2004). "Lysozyme and complement response to exercise in horses with booster vaccination against influenza virus and equine herpes virus 1 and 4." Revue de Medecine Veterinaire 155(8/9): 449–452.
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