Thrombolytic Therapy in the Acute Period of Aortic Thromboembolism in Cats

  • Joshua Billy Hannabuss University of Bristol, Bristol Veterinary School, Langford House, Langford, Bristol BS40 5DU

Published:

2019-06-06

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DOI

https://doi.org/10.18849/ve.v4i2.212

Abstract

PICO question

Of cats that present with aortic thromboembolism, do patients that receive thrombolytic therapy in the acute phase have improved survival as compared to those who do not?

Clinical bottom line

Based on the current available evidence, the use of thrombolytic therapy in the acute phase of aortic thromboembolism (ATE) does not appear to improve survival when compared to conventional supportive therapy. Frequently reported adverse side effects further questions its merits, and large scale controlled clinical trials would be required to further evaluate any benefit in the use of this therapy.


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References

Borgeat, K., Wright, J., Garrod, O., Payne, J.R., and Fuentes, V.L. (2014). Arterial thromboembolism in 250 cats in general practice: 2004–2012. Journal of Veterinary Internal Medicine. 28, 102–108. DOI: https://doi.org/10.1111/jvim.12249

Moore, K.E., Morris, N., Murtaugh, R.J., and Rush, J.E. (2000). Retrospective Study of Streptokinase Administration in 46 Cats with Arterial Thromboembolism. Journal of Veterinary Emergency and Critical Care. 10 (4), 245–257. DOI: https://doi.org/10.1111/j.1476-4431.2000.tb00010.x

Reimer, S.B., Kittleson, M.D., and Kyles, A.E. (2006). Use of Rheolytic Thrombectomy in the Treatment of Feline Distal Aortic Thromboembolism. Journal of Veterinary Internal Medicine. 20, 290–296. DOI: https://doi.org/10.1111/j.1939-1676.2006.tb02859.x

Schoeman, J.P. (1999). Feline distal aortic thromboembolism: a review of 44 cases (1990–1998). Journal of Feline Medicine and Surgery. 1 (1), 221–231. DOI: https://doi.org/10.1053/jfms.1999.0049

Smith, S.A., Tobias, A.H., Jacob, K.A., Fine, D.M., and Grumbles, P.L. (2003). Arterial Thromboembolism in Cats: Acute Crisis in 127 Cases (1992–2001) and Long-Term Management with Low-Dose Aspirin in 24 Cases. Journal of Veterinary Internal medicine. 17, 73–83. DOI: https://doi.org/10.1111/j.1939-1676.2003.tb01326.x

Welch, K.M., Rozanski, E.A., Freeman, L.M., Rush, J.E. (2010). Prospective evaluation of tissue plasminogen activator in 11 cats with arterial thromboembolism. Journal of Feline Medicine and Surgery. 12, 122–128. DOI: https://doi.org/10.1016/j.jfms.2009.08.001

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Vol. 4 No. 2 (2019): The second issue of 2019

Section: Knowledge Summaries

Categories :  Small Animal  /  Dogs  /  Cats  /  Rabbits  /  Production Animal  /  Cattle  /  Sheep  /  Pig  /  Equine  / 

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